Background Biomedical and ethnographic studies among indigenous people are common practice in health and geographical research. Prior health research misconduct has been documented, particularly when obtaining genetic material. The objective of this study was to crossmatch previously published data with the perceptions of the Waorani peoples about the trading of their genetic material and other biological samples. Methods We conducted a mixed methods study design using a tailored 15-item questionnaire in 72 participants and in-depth interviews in 55 participants belonging to (...) 20 Waorani communities about their experiences and perceptions of participating in biomedical research projects. Additionally, we conducted a systematic review of the literature in order to crossmatch the published results of studies stating the approval of an ethics committee and individual consent within their work. Results A total of 40 men and 32 women, with a mean age of 57 ± 15 years agreed to be interviewed for inclusion. Five main categories around the violation of good clinical practices were identified, concerning the obtention of blood samples from a recently contacted Waorani native community within the Amazonian region of Ecuador. These themes are related to the lack of adequate communication between community members and researchers as well as the voluntariness to participate in health research. Additionally, over 40 years, a total of 38 manuscripts related to the use of biological samples in Waorani indigenous people were published. The majority of the studies did not state within their article obtaining research ethics board approval, and 71% did not report obtaining the informed consent of the participants prior to the execution of the project. Conclusion Clinical Research on the Waorani community in the Ecuadorian Amazon basin has been performed on several occasions. Unfortunately, the majority of these projects did not follow the appropriate ethical and professional standards in either reporting the results or fulfilling them. The results of our investigation suggest that biological material, including genetic material, has been used by researchers globally, with some omitting the minimum information required to guarantee transparency and good clinical practices. We highlight the importance of stating ethics within research to avoid breaches in research transparency. (shrink)

Reseña de: Arenas-Dolz, Francisco y Gallegos Salazar, Daniela (eds.) (2009), El ciudadano democrático. Reflexiones éticas para una educación intercultural, Madrid, Plaza y Valdés.

The area of smart power grids needs to constantly improve its efficiency and resilience, to provide high quality electrical power in a resilient grid, while managing faults and avoiding failures. Achieving this requires high component reliability, adequate maintenance, and a studied failure occurrence. Correct system operation involves those activities and novel methodologies to detect, classify, and isolate faults and failures and model and simulate processes with predictive algorithms and analytics. In this paper, we showcase the application of a complex-adaptive, self-organizing (...) modeling method, and Probabilistic Boolean Networks, as a way towards the understanding of the dynamics of smart grid devices, and to model and characterize their behavior. This work demonstrates that PBNs are equivalent to the standard Reinforcement Learning Cycle, in which the agent/model has an interaction with its environment and receives feedback from it in the form of a reward signal. Different reward structures were created to characterize preferred behavior. This information can be used to guide the PBN to avoid fault conditions and failures. (shrink)

"La filosofía en Puerto Rico: los transterrados reúne varios estudios sobre filófofos extranjeros que en algún momento decidieron compartir su vida, su enseñanza y sus trabajos académicos con los habitantes de esta bella y hospitalaria Isla de Puerto Rico. La presente es una obra en la cual han colaborado varios autores: Manfre Kerkhoff, Antonio Mansilla Triviño, Juan José Sánchez, Luis Ramírez, José Rivera y Carlos Rojas Osorio, quien estuvo a cargo la iniciativa, el plan de la obra (...) y la edición."--Cubierta. (shrink)

Resumen:Con el objetivo de pensar lo político y su “conflicto originario” (19) –tema que viene inquietando a Juan Pablo Arancibia desde hace tiempo–, la recuperación de dos nociones griegas permite penetrar en una relación que vendría a desestabilizar o a incomodar nuestro presente “tornando insuficientes –dice– aquellas respuestas normativas provistas por la tradición” (19), en particular –agrega– aquella “confortable representación de la historia del orden y su porvenir” (21).

Con el objetivo de pensar lo político y su “conflicto originario” (19) –tema que viene inquietando a Juan Pablo Arancibia desde hace tiempo–, la recuperación de dos nociones griegas permite penetrar en una relación que vendría a desestabilizar o a incomodar nuestro presente “tornando insuficientes –dice– aquellas respuestas normativas provistas por la tradición” (19), en particular –agrega– aquella “confortable representación de la historia del orden y su porvenir” (21).

Using Koszmider's strongly unbounded functions, we show the following consistency result: Suppose that κ, λ are infinite cardinals such that κ++ + ≤ λ, κ<κ = κ and 2κ = κ+, and η is an ordinal with κ+ ≤ η < κ++ and cf = κ+. Then, in some cardinal-preserving generic extension there is a superatomic Boolean algebra equation image such that equation image, equation image for every α < η and equation image. Especially, equation image and equation image can (...) be cardinal sequences of superatomic Boolean algebras. (shrink)

Frecuentemente se ha interpretado la filosofía política de Julien Freund como una lectura decisionista y polemocéntrica de lo político de fuertes ecos schmittianos. Sin entrar en sus raíces intelectuales, pretendo justificar el sentido que asume en su obra la adhesión a la tradición realista, distanciándose sin embargo de una interpretación tanto cratológica como nihilista de la política que tendiera a reducir los asuntos públicos al solo dominio estratégico de los medios. Entiendo, al contrario, que el realismo de Freund coincide con (...) su perspectiva “mesocrática” o, si se prefiere, “liberal” en un sentido “árquico”, no minarquista o neutralizador. Esto exige un cambio de enfoque en el estudio de su obra que evite fundamentalmente dos extremos: la reducción de lo político a la sola dialéctica del mando y la obediencia, a costa de la integración de todos sus factores, y la sobrevaloración del problema de los medios respecto de los fines. (shrink)

O presente trabalho é uma tradução do espanhol para o português de três contos do livro "Cuentos de Amor de Locura y de Muerte" do escritor uruguaio Horacio Quiroga. Os contos selecionados são: "La Gallina Degollada", "El Almohadón de Plumas" e "A la Deriva". Os textos traduzidos ficaram com os seguintes nomes: "A Galinha Degolada" "O Travesseiro de Penas" e "À Deriva".

La experiencia filosófica de Pablo Posada Varela queda lejos de ser un currículo de filósofo académico. Cuando el verdadero filósofo escribe está movido siempre por motivaciones éticas, para fortalecer el sentido que se busca. Un sentido en contacto permanente con su φρενός, una «inteligencia frenética» al margen de los espasmos del cogito cartesiano y su posterior narcosis. Tampoco ese sentido tiene que ver con la búsqueda de la verdad de su perpetuum mobile. En Pablo Posada Varela hay una verdadera topología (...) del sentido, ideas del sentido fuera del sentido. (shrink)

El propósito de esta entrada es hacer notar la inquietud de Marc Richir en sus Méditations phénoménologiques (1992: 61), de que una estética fenomenológica era más necesaria que nunca aun moviéndonos en cualquier horizonte, imposible de hecho, como a veces pueda serlo el lenguaje en busca del sentido; pero esta entrada se enmarca en una parrhesía de lenguaje más bien débil centrada en lo antiguo donde el arte, (tomando como referencia o inicio (ὑπάρχω) las tragedias griegas en el plano de (...) la mímesis, en correspondencia con la Einfühlung, identificación fenomenológica, la identidad de la obra en las tragedias), tanto si imita sólo con lenguaje (arte de la sofística), como si se habla de la verdadera creación, la tragedia, sobrepasa las etiquetas de cualquier logos en permanente lucha: trágico, intencional, pasional o trascendental; no encontramos ninguna mitología semántica que lo identifique en una cerca intencional, por su pérdida espontánea, o lo recupere en un sentido estético incoativo, en una fase (φάσις), o forma que dejará ver o no según le dé la luz; Platón no lo llega a cazar en el Sofista (al arte de la sofística), porque transgrede cualquier conducta, desde dentro y desde fuera, es decir, tanto si es un disimulo pasional del poeta (catarsis antigua), como si lo consideramos desde el marco de Aristóteles en el cierre artístico clásico de la tragedia (symmetría) en la experiencia generada en el espectador como un fenómeno estético insuficiente (catarsis trágica). (shrink)

With the advent of the cloud computing model allowing a shared access to massive computing facilities, a surging demand emerges for the protection of the intellectual property tied to the programs executed on these uncontrolled systems. If novel paradigm as confidential computing aims at protecting the data manipulated during the execution, obfuscating techniques (in particular at the source code level) remain a popular solution to conceal the purpose of a program or its logic without altering its functionality, thus preventing reverse-engineering (...) on the program even with the help of computing resources. The many advantages of code obfuscation, together with its low cost, makes it a popular technique. This paper proposes a novel methodology for source code obfuscation that can be used together with other traditional obfuscation techniques, making the code more robust against reverse engineering attacks. Three program complexity metrics are used to define three different single-objective combinatorial optimization versions of the problem, which are solved and analysed. Additionally, three multi-objective problems are defined, those considering each of the selected metrics together with the program execution time, in order to avoid strong obfuscations penalizing the performance. The goal of the defined problems is to find sequences of LLVM optimizations that lead to highly obfuscated versions of the original code. These transformations are applied to the back-end pseudo-assembly code (i.e., LLVM Intermediate Representation), thus avoiding any further optimizations by the compiler. Classical genetic algorithms (GAs) are used to solve the studied problems, namely a basic cellular GA for the single-objective problems and the popular NSGA-II for the multi-objective ones. The promising results show the potential of the proposed technique. (shrink)

Los escritos de Jürgen Habermas han despertado en España un interés notable y sostenido en el tiempo. Han ejercido una fuerte influencia intelectual no solo en los círculos académicos, sino también en amplios sectores de la esfera pública, algo sorprendente teniendo en cuenta su complejidad y su carácter más bien técnico. En sus textos los lectores españoles han encontrado elementos que sintonizan constructivamente con los cambios acaecidos en su propia sociedad y en el mundo. Como argumento de autoridad o como (...) referencia a rebatir, Habermas se ha hecho habitual en la filosofía y en la teoría social pensada y escrita en español. En este artículo se tratará de presentar los diversos contextos que posibilitaron la acogida de sus ideas, así como los principales actores que con sus trabajos y reflexiones han protagonizado la propagación de su pensamiento. (shrink)

The purpose of this article is making a critical revision of the field of communication –understood as a field of research and reflection– and the way its existence has been tried to be legitimated since the postwar period. Our stance holds that, even though it is possible to find relatively linear and continuous narratives to understand communication, what is regarded here is reaching comprehension of the fragmentation and language games brought together in it. Besides, the core problem does not rely (...) on the consolidation of a linear and scientific epistemological narrative, but on the manner discourse is articulated, giving place to such narratives turning around their political charges and not the supposed scientific value attributed to them. (shrink)

By using the notion of a simplified (κ,1)-morass, we construct κ-thin-tall, κ-thin-thick and, in a forcing extension, κ-very thin-thick superatomic Boolean algebras for every infinite regular cardinal κ.

La selección natural ayuda a resolver el misterio de la vida pero no es aplicable para explicar la diversidad cultural. La selección natural es vista, por una parte, como un componente de la imaginación de un mundo industrial cambiante, y, por la otra, como un medio de producir diferencias en el seno de procesos sociales que son claves en la distribución de los genes humanos. La genética es intencionalmente traducida en el mundo social: se subvierte la biología y se la (...) somete a la agencia humana. Tal es una ruptura esencial que enmarca el reservorio genético en el novedoso mundo humano. Los seres humanos deliberan acerca de su condición y, al hacerlo, cooptan la naturaleza. No obstante, esto no es un proceso evidente sino que en sí mismo está infiltrado por los procesos neurológicos, una poderosa razón para mantener una visión dialéctica de la relación entre los genes y los humanos. (shrink)

The Lasallian District of Medellin, Colombia requested Corporación Universitaria Lasallista to analyze the formation process received by postulants to De La Salle Brothers in Istmina, Colombia, from 2002 to 2010. Academic, religious, pedagogical, apostolic and personal formation experiences received there were analyzed in this case study –from a qualitative approach– by means of semi-structured interviews and focus groups. Personal and apostolic formations stand out among the results due to the characteristics of Istmina as a proper place for sensibilization and subjugation (...) in proof of vocation. However, the reach of integral formation is questioned because academic formation presented meaningful deficiencies. In conclusion, even though formation experiences in vulnerable contexts are appreciated –and contextualization of learning is deemed meaningful–, participants agree in the necessity of developing strong competences to face educational and apostolic practices. (shrink)

Though laughter and smiles are a part of our everyday lives, they are not always used appropriately. We need to learn how to laugh, to educate our sense of humor. This book is a meditation on humor in general, the humor we deploy and perceive on a day-to-day basis, and on the ethical dimensions that underpin it. It puts forward a new ethical theory, placing humor at the Archimedean point from which to further our understanding as moral subjects, offering explanations (...) as to our moral conduct and pointing the way towards ethical improvement as both individuals and as a group. After defining what humor is and portraying the current state of play among experts on the subject, the author sets out based on the major contributions made by the great philosophers. Then, taking in such fundamental ethical categories as moral sentiment, virtue, duty, capacity and responsibility, he puts forward his own ethical theory (what he refers to as the ethics of humor), based on both linguistic and biological rational. He unveils a new medical/philosophical method: clinical ethics, capable of interpreting humor as a point where ethics and health intersect. This volume also points out various means by which this ethical theory might be brought to bear on fields such as healthcare, business, education, politics, the mass media and everyday life. Above all, it discovers the role that good humor has to play in health and the instruments used to measure it. Juan Carlos Siurana argues that good humor gives expression to freedom, is universal, and contains within itself the basis of a cross-cultural ethical approach, one that is well worth understanding and teaching. Given that humor crosses over into every dimension of our personal and professional lives, the book is aimed at a broad, multidisciplinary public (philosophers, medical practitioners, nurses, company executives, teachers, politicians, psychologists, journalists, etc.), as well as anyone with an interest in the various registers of humor. He offers both theoretical and practical tools for the ethical improvement of professions, organizations and the public at large. (shrink)